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Pharm Sci. 2024;30(4): 398-422. doi: 10.34172/PS.2024.24

Review Article

Unveiling the Biomedical Applications of Zinc Oxide (ZnO) Nanoparticles: A Review Fostering on the Synthesis, Therapeutics and Imaging with Recent Developments

Zenli Cheng 1 * ORCID, Ashok Kumar Janakiraman 1 * ORCID, Baskaran Gunasekaran 2 ORCID, Crystale Lim Siew Ying 2 ORCID, Ezanee Azlina Binti Mohamad Hanif 3 ORCID, Hanish Singh Jayasingh Chellammal 4 ORCID, Sinouvassane Djearamane 5 ORCID

Cited by CrossRef: 2


1- Dhanush G, Praveen Kumar C, Pramoda K, Vivek H, Girish Y. 2-Dimensional black phosphorus nanostructures for biomedical applications. Materials Today Nano. 2026;33:100763 [Crossref]
2- Gupta A, Kirti A, Sahu R, Lenka S, Yadav A, Choudhury A, Sinha A, Nandi A, Mohakud N, Patro S, Ghosh A, Kaushik N, Suar M, Verma S. Translational paradigm in nanodiagnostics applications of functionalized zinc oxide nanoforms interface for pathogenic virus diagnostics. Chemical Engineering Journal. 2025;509:161260 [Crossref]
3- Prakash R, Saravanan P, Kumar P, Omer S, Rajeshkannan R, Kumar S. Synergistic green synthesis of ZnO nanoparticles using Cymbopogon citratus and Nelumbo nucifera for enhanced antibacterial activity. Sustainable Chemistry One World. 2025;8:100144 [Crossref]
4- Aldosari H. A Critical Review on Zinc Oxide Nanoparticles (ZnO NPs) Bio Applications and Toxicities Mechanisms. NHC. 2025;48:11 [Crossref]
5- Kumar S, Chauhan N, Chopra S, Bhatia A. Nanocarriers and Nanomaterials in Dentistry: A Review on Common Dental Issues and their Management. CPD. 2025;31(29):2315 [Crossref]
6- Azzi M, Laib I, Bouafia A, Benaissa A, Medila I, Houmri N, AL‐Farga A, Laouini S. ZnO Nanoparticles Derived From Olea europaea Leaves With Potent Antimutagenic, Antioxidant, and Antibacterial Activities via Green Synthesis. ChemistrySelect. 2026;11(1) [Crossref]
7- Venkadajalapathy V, Sanjay L, Ramalingam B, Robert S, Robert K, Sivaramakrishnan S. Dap-ZnO composite: A novel dermocosmetic solution derived from Fusarium oxysporum, an endophytic fungus of Brown algae. Biocatalysis and Agricultural Biotechnology. 2025;70:103792 [Crossref]
8- Sayeem N, Podder U, Alam M, Shishir M, Miah M, Anik F, Ghosh P, Ahmed S, Islam M, Jahan S. Critical perspective review on green synthesis of zinc oxide nanoparticles: Explored wurtzite phase, characterization and real world applications. Next Nanotechnology. 2026;9:100412 [Crossref]
9- Siddiqui M, Azam M, J. P. S, Kumar S, Prasad R, Alomary M, Ansari M, Alharbi H, Alhumaidi M, Peana M. Phytofabrication of Zinc Oxide Nanoparticles Using Sida cordifolia L. and Their Biomedical Applications. Bioinorganic Chemistry and Applications. 2026;2026(1) [Crossref]
10- Cheng Z, Janakiraman A, Sundarapandian R, Djearamane S, Jayasingh Chellammal H, Ahamed H, Kayarohanam S. Precision engineering of vinblastine-loaded zinc oxide nanoparticles through statistical experimental design. Nano-Structures & Nano-Objects. 2025;42:101472 [Crossref]
11- Fatiha R, Ngabdi C, Azizah J, Lestari B, Malek N, Permatasari H. Metallic nanoparticles in cervical cancer therapy: A molecular perspective on modulating sensitivity to conventional treatments. Particuology. 2026;113:264 [Crossref]
12- Jagajeevan V, Sivakumar V. Surface-engineered ZnO air filters for the capture and quantitative detection of PM₂.₅ in urban environments. Progress in Engineering Science. 2026;3(1):100225 [Crossref]

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